Nuclear Medicine and Biology · 2000 · 127 citations · 25 references
MedicineHematologyMolecular BiologyHemostasisMolecular DiagnosticsTransfusion MedicineAnticoagulant TherapyAnticoagulation TherapyHemostatic AgentsOligonucleotide ChemistryThrombosisThrombosis PreventionAptamer StabilityAptamer-based BiosensingAptamers
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Selection of single-stranded DNA molecules that bind and inhibit human thrombin
Louis C. Bock, Linda C. Griffin, John Latham et al. · Nature · 1992 · 2.5K citations
Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes
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