Inclusion Disease in Childhood

Abstract

enlarged to a diameter of 20-40[L so that they are two to four times as large as unaffected cells (Fig. Most authors point out that transitions from normal to abnormal cells are rarely if ever seen, although stages in the development of the inclusion bodies have been described (Cappell and McFarlane, 1947). Often there is a condensation of the cytoplasm to form a thick refractile cell membrane, a feature most prominent in those cells showing evidence of degeneration.