CHIMIA International Journal for Chemistry · 1994 · 46 citations · 0 references
Chiral AminesLipase Candida AntarcticaEngineeringBiochemistryKinetic ResolutionBiocatalysisNatural SciencesEnzyme CatalysisChiral Primary AminesCatalysisEnzymatic ModificationAsymmetric CatalysisEnantioselective SynthesisBiomolecular Engineering
The lipase Candida antarctica catalyzes the enantioselective acetylation of chiral primary amines, kinetic resolution leading to an enantiomeric excess (ee) of 90–98%.