Palladium‐Mediated Annulation of Vinyl Aziridines with Michael Acceptors: Stereocontrolled Synthesis of Substituted Pyrrolidines and Its Application in a Formal Synthesis of (−)‐α‐Kainic Acid

Abstract

Salz nicht vergessen: In Gegenwart von Pd0 cyclisieren Vinylaziridine mit Methylvinylketon oder Ethylthioacrylat mit mäßigen bis guten Diastereoselektivitäten zu Pyrrolidinen – allerdings nur bei Zugabe des Salzes nBu4NCl. Die Methode wurde in einer kurzen (formalen) Synthese von (−)-α-Kainsäure angewendet. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.