Chemical and Pharmaceutical Bulletin · 1960 · 18 citations · 0 references
MedicineBiochemistryPharmacologyBiochemical PharmacologyDrug MetabolismDrug DispositionMetabolite IdentificationRabbit PharmacologyDrug Excretion In RabbitsDrug Metabolism In RabbitsHydroxybenzoic AcidsPaper Chromatography
The ether-type glucuronide of p-hydroxybenzoic acid was isolated as methylacetyl derivative from the urine of rabbits receiving methyl p-hydroxybenzoate and its structure was established as methyl (p-methoxycarbonylphenyl 2, 3, 4-tri-O-acetyl-β-D-glucopyranosid)-uronate with the synthetic sample. Ester-type glucuronide was detected in the urine by paper chromatography.