The Vinyl Moiety as a Handle for Regiocontrol in the Preparation of Unsymmetrical 2,3‐Aliphatic‐Substituted Indoles and Pyrroles

Abstract

Mit einem Rhodiumkatalysator gelingt die regioselektive oxidative Kupplung von Eninen mit N-Arylharnstoffen (X=NR2) und N-Vinylacetamiden (X=C(O)Me) unter Bildung der jeweiligen 2-Alkenylindole und 2-Alkenylpyrrole in guten Ausbeuten. Eine einfache Hydrierung ergibt die aliphatisch an der C2/C3-Position substituierten Indole bzw. Pyrrole (siehe Schema). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.