The American Journal of Gastroenterology · 1999 · 22 citations · 4 references
PharmacyImmunologyInfectious DiseasesHepatic PharmacotherapyImmunopathologyIron Metabolism DisordersAntiviral TherapyInterferon ResponsesInterferon-based TherapyIron DeficiencyLiver DiseaseViral HepatitisChronic Viral HepatitisHepatitis C Virus ManagementInternal Pilot Study DesignPilot Study DesignPilot Study PlanningPilot Study Sample SizeType Ii Interferon Response
The aim of this study was to assess the efficacy of iron depletion obtained by phlebotomy to enhance interferon response in 11 patients who had failed to respond to a standard 3-month interferon treatment. Despite a significant effect on serum aminotransferase levels, there was no effect on viremia, and iron depletion was unable to trigger interferon response.
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