Improvement of serum aminotransferase levels after phlebotomy in patients with chronic active hepatitis C and excess hepatic iron.

Hisao Hayashi, Toshikuni Takikawa, N Nishimura, +3

PubMed

Long term effects of phlebotomy on biochemical and histological parameters of chronic hepatitis C

Motoyoshi Yano, Hisao Hayashi, Shinya Wakusawa, +8

The American Journal of Gastroenterology

Iron accumulation in the liver of male patients with Wilson's disease

Yuhta Shiono, Shinya Wakusawa, Hisao Hayashi, +6

The American Journal of Gastroenterology

Mutational analysis ofATP7Band genotype-phenotype correlation in Japanese with Wilson's disease

Toshihide Okada, Yuta Shiono, Hisao Hayashi, +8

Human Mutation

Patients with chronic hepatitis C achieving a sustained virological response to peginterferon and ribavirin therapy recover from impaired hepcidin secretion

Naoki Fujita, Ryosuke Sugimoto, Satoshi Motonishi, +8

Journal of Hepatology

HepatologyHepatitis CHepcidin SecretionViral HepatitisAntiviral Therapy +6

Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells

Sakiko Arisawa, Kumiki Ishida, Natsumi Kameyama, +10

Biochemical Pharmacology

Reductive StressBiochemistryCell SignalingHepg2 CellsMedicine +11

A significant reduction in serum alanine aminotransferase levels after 3-month iron reduction therapy for chronic hepatitis C: a multicenter, prospective, randomized, controlled trial in Japan

Motoyoshi Yano, Hisao Hayashi, Kentaro Yoshioka, +18

Journal of Gastroenterology

HepatologySignificant ReductionViral HepatitisIron MetabolismLiver Physiology +5

Serum aminotransferase levels as an indicator of the effectiveness of venesection for chronic hepatitis C

Hisao Hayashi, Toshikuni Takikawa, Noriko Nishimura, +1

Journal of Hepatology

HepatologyHepatitis CSerum Aminotransferase LevelsViral HepatitisLiver Physiology +6

Two novel mutations, L490R and V561X, of the transferrin receptor 2 gene in Japanese patients with hemochromatosis.

Chizu Koyama, Shinya Wakusawa, Hisao Hayashi, +7

PubMed

Three patients with middle-age-onset hemochromatosis caused by novel mutations in the hemojuvelin gene

Chizu Koyama, Hisao Hayashi, Shinya Wakusawa, +5

Journal of Hepatology

Mendelian DisorderGenetic DisorderGeneticsHematologyHemojuvelin Gene +6