Computational analysis for the determination of deleterious nsSNPs in human MTHFR gene

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Structure validation by Cα geometry: ϕ,ψ and Cβ deviation

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CDD: NCBI's conserved domain database

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Predicting the Functional Effect of Amino Acid Substitutions and Indels

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A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

James U. Bowie, Roland Lüthy, David Eisenberg · Science · 1991 · 2.9K citations

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