Lactase Enzyme, Detected Immunohistochemically, Is Lost in Active Celiac Disease, But Unaffected by Oats Challenge

Abstract

The immunohistochemical technique used in this study provides an easy, reliable method of assessing lactase enzyme and confirms the value of this index as a marker of celiac disease activity. The results of two recent studies demonstrating the lack of oats toxicity in adult celiac patients have been further corroborated by our findings, which show the preservation of lactase enzyme after oats challenge.