Concepedia

Synthesis of Oligo-N-methylpyrrolecarboxamide Derivatives and Their Photochemical DNA Cleaving Activities

Masayuki Shibuya, Eiji Nishiwaki, Hirofumi Nakagawa, Michika Takasaki, Toyomi MATSUMOTO, Hiromu Sakurai

Heterocycles · 1990 · 19 citations · 0 references

Open access

Concepts

PharmacyChemistryMolecular BiologyDna RepairNucleic Acid ChemistryDna ChemistryDna DamageOligonucleotide ChemistryPhotochemical SynthesisChemical Modification Of OligonucleotidesOligonucleotide Cleavage ChemistryOligonucleotide SynthesisPhotocleavage Of Nucleic AcidsRepair Of Uv-induced Dna DamageUltraviolet-induced Dna DamageUv-induced Dna Lesions

Abstract

Synthesis of various oligo-N-methylpyrrolecarboxamide derivatives and their DNA cleaving activities under UV-A irradiation were described.