Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto, +9

Science

Tissue EngineeringAdult Stem CellTransplantation MedicineRegenerative MedicineHuman Somatic Cells +16

High-Resolution Profiling of Histone Methylations in the Human Genome

Artem Barski, Suresh Cuddapah, Kairong Cui, +6

Cell

Histone ModificationsChromatinHistone MethylationsEpigenetic ChangeGenetics +5

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, +12

Cell

ChromatinDevelopmental BiologyChromatin StructureChromatin RemodelingMedicine +11

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lee P. Lim, Nelson C. Lau, Philip W. Garrett-Engele, +6

Nature

Target MrnasSystems BiologyFunctional GenomicsMedicineGenetics +11

Combinatorial microRNA target predictions

Azra Krek, Dominic Grün, Matthew N. Poy, +8

Nature Genetics

Systems BiologyFunctional GenomicsGeneticsMicrorna DetectionSmall Rna +4

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Laurie A. Boyer, Tong Ihn Lee, Megan F. Cole, +11

Cell

Transcriptional RegulationDevelopmental BiologyMedicineAdult Stem CellStem Cell Research +4

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe, +19

Nature

ChromatinChromatin StructureChromatin StateChromatin RemodelingNatural Sciences +10

MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing

Andrew Grimson, Kyle Kai‐How Farh, Wendy K. Johnston, +3

Molecular Cell

GeneticsMicrorna Targeting SpecificityMicrorna DetectionSmall RnaGene Expression +3

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

Pablo Landgraf, Mirabela Rusu, Robert P. Sheridan, +48

Cell

Systems BiologyFunctional GenomicsEngineeringGeneticsComputational Biology +7

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Hitoshi Niwa, Jun‐ichi Miyazaki, Austin Smith

Nature Genetics

Embryonic Stem CellCell LineageQuantitative ExpressionDevelopmental BiologyOct-3/4 Defines Differentiation +7