Green Sample Preparation Techniques for Chromatographic Determination of Small Organic Compounds

Abstract

Accurate monitoring of the state of the environment requires the introduction of additional isolation and/or preconcentration step prior to the chromatographic determination. In this work the information about novel methodological and instrumental solutions in relation to different variants of microextraction techniques are presented. Attention is focused on analytical procedure and suitable analytical tools for extraction of the analytes from samples with a complex matrix composition and on minimazing of organic solvent consumption. The described modifications of extraction techniques deal with system miniaturization and/or automation, the use of additional agents to enhance the effectiveness of extraction like ultrasound and physical agitation, and electrochemical methods. Particular attention was given to pro-ecological aspects therefore the possible use of novel, non-toxic extracting agents and selective sorbents have been evaluated in depth.