Publication | Closed Access
DNA Aptamer‐Mediated Cell Targeting
36
Citations
25
References
2012
Year
Pharmaceutical ScienceMolecular BiologyGene DeliveryNucleic Acid BiomarkersBioanalysisClinical ChemistryOnline DeliveryBiochemistryDna ReplicationChemical PathologyDna-aptameren Versehen WerdenDrug DevelopmentPharmacologyCell BiologyNatural SciencesGelungene ModifizierungMedicineGenome EditingDrug DiscoveryPharmaceutical Research
Gelungene Modifizierung: Zelloberflächen können auf einfache Weise mit zielspezifischen Liganden wie DNA-Aptameren versehen werden, wobei die Auswirkungen auf die modifizierten Zellen minimal gehalten werden. Nach Inkubation mit Lipoaptamer-Sonden erkennen Immunzellen (rot, siehe Schema) in einer Zellmischung Krebszellen (blau) und zerstören diese. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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