Rescue GPi-DBS for a Stroke-associated Hemiballism in a Patient with STN-DBS - Concepedia

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Rescue GPi-DBS for a Stroke-associated Hemiballism in a Patient with STN-DBS

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2014

Year

Genko Oyama, Nicholas Maling, Amanda Avila-Thompson, Pam Zeilman, Kelly D. Foote, Irene A. Malaty, Ramon L. Rodriguez, Michael S. Okun

Tremor and Other Hyperkinetic Movements

Basal GangliaNeurological DisorderBilateral Subthalamic NucleusNeuromodulation TherapiesClinical NeurologyCerebrovascular DiseaseBrain LesionNeurovascular DiseaseThrombosisStroke RehabilitationNeurobiology Of DiseaseStrokeHematologyNeurologyBleeding DisorderPublic HealthNeuropathologyStroke-associated HemiballismBasal Ganglia PhysiologyNeuroepidemiologyNeurological MonitoringRehabilitationRescue Gpi-dbsCerebral Blood FlowMovement DisordersLead ImplantationCardiovascular DiseaseNeurophysiologyNeuroanatomyStroke-related ConditionNeuroscienceMultiple SclerosisCentral Nervous SystemMedicineEmergency Medicine

Abstract

<strong>Background:</strong> Hemiballism/hemichorea commonly occurs as a result of a lesion in the subthalamic region. <strong>Case Report:</strong> A 38-year-old male with Parkinson’s disease developed intractable hemiballism in his left extremities due to a small lesion that was located adjacent to the right deep brain stimulation (DBS) lead, 10 months after bilateral subthalamic nucleus (STN)-DBS placement. He underwent a right globus pallidus internus (GPi)-DBS lead implantation. GPi-DBS satisfactorily addressed his hemiballism. <strong>Discussion:</strong> This case offered a unique look at basal ganglia physiology in human hemiballism. GPi-DBS is a reasonable therapeutic option for the treatment of medication refractory hemiballism in the setting of Parkinson’s disease.