Clinical efficacy and safety of polynucleotides highly purified technology (<scp>PN‐HPT</scp>®) and cross‐linked hyaluronic acid for moderate to severe nasolabial folds: A prospective, randomized, exploratory study

Abstract

Although conceived only as an exploratory investigation, the study confirmed that PN-HPT® monotherapy might be a valuable and effective option to rapidly improve the skin dermis texture and quality in individuals with moderate to severe NLFs. Acting as a priming agent in the skin, PN-HPT® prolong the clinical efficacy of cross-linked HA. Well-designed trials in larger treatment groups will hopefully confirm these early promising results.