Pharmacological activation of estrogenic receptor G protein-coupled receptor 30 attenuates angiotensin II-induced atrial fibrosis in ovariectomized mice by modulating TGF-β1/smad pathway

Sex Differences and Similarities in Atrial Fibrillation Epidemiology, Risk Factors, and Mortality in Community Cohorts

Christina Magnussen, Teemu Niiranen, Francisco Ojeda et al. · Circulation · 2017 · 445 citations · Full text

Medicine, Cardiology, Clinical Epidemiology +16

Mir-21 Promotes Cardiac Fibrosis After Myocardial Infarction Via Targeting Smad7

Jinxia Yuan, Hongtao Chen, Dawei Ge et al. · Cellular Physiology and Biochemistry · 2017 · 221 citations · Full text

Life Sciences, Cardiology, Molecular Biology +14

AGEs activate mesangial TGF-β–Smad signaling via an angiotensin II type I receptor interaction

Kei Fukami, Seiji Ueda, Sho‐ichi Yamagishi et al. · Kidney International · 2004 · 217 citations · Full text

Life Sciences, Pharmacology, Cell Signaling +9

Pirfenidone alleviates pulmonary fibrosis in vitro and in vivo through regulating Wnt/GSK-3β/β-catenin and TGF-β1/Smad2/3 signaling pathways

Qun Lv, Jianjun Wang, Changqing Xu et al. · Molecular Medicine · 2020 · 198 citations · Full text

Veterinary Medicine, Pharmacology, Pharmacotherapy +16

A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury

Jean C. Bopassa, Mansoureh Eghbali, Ligia Toro et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2009 · 195 citations · Full text

Medicine, Cardiology, Pharmacology +15