Enantioselective intramolecular Pictet–Spengler type annulation of indole-linked 3-methyleneisoindolin-1-ones

Abstract

Asymmetric intramolecular Pictet–Spengler type annulation of indole-linked 3-methyleneisoindolin-1-ones provided isoindolinone fused tetrahydro β-carbolines with moderate to good enantioselectivities.