Bioglass: A New Era in Modern Dentistry

Abstract

Abstract The function of biomaterials has been to replace infected or injured tissues. The first used biomaterials were bioinert, thus minimizing formation of scar tissue at the interface with host tissues. Bioglass was discovered in 1969. Larry Hench developed Bioglass 45S5, which was the earliest synthetic substance that was bonded chemically with bone. In recent researches it has appeared that Bioglass bonds with bone more readily than other bioceramics; it also indicated that the osteogenic properties are due to stimulation of osteoprogenitor cells by the dissolution products formed from Bioglass. Bioglass is chemically calcium sodium phosphosilicate, which is capable of forming an active chemical bond with the tissues. Bioglass is particularly biocompatible which, when placed in body cavity or on reacting with body stimulating factors, induces hydroxyapatite formation. This paper reviews Bioglass as a material of modern dentistry and its various applications in modern dentistry. It also discusses its composition, methods of preparation, and mechanism of action, along with its advantages and disadvantages.