Concepedia

Publication | Open Access

Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis

DOIFull Paper Access

71

Citations

39

References

2022

Year

Kaori Endo‐Umeda, Eun Young Kim, David G. Thomas, Wenli Liu, Huijuan Dou, Mustafa Yalçınkaya, Sandra Abramowicz, Tong Xiao, Per Antonson, Jan-Ακε Gustafsson,
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Our current studies reveal the key role of macrophage LXRs in promoting the <i>Trem2</i> gene expression program and in suppressing inflammation in foam cells of atherosclerotic plaques.

References

YearCitations

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