Concepedia

SOCS1 counteracts ROS-mediated survival signals and promotes apoptosis by modulating cell cycle to increase radiosensitivity of colorectal cancer cells

Ji‐Yoon Ryu, Jiyoung Oh, Sumin Kim, Won-Gi Kim, Shinae Ahn, Seol-Hee Kim, Ji-Young Jang, Byong Chul Yoo, Chul Woo Kim, Choong‐Eun Lee

BMB Reports · 2022 · 11 citations · 23 references

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Abstract

Ji-Yoon Ryu, Jiyoung Oh, Su-Min Kim, Won-Gi Kim, Hana Jeong, Shin-Ae Ahn, Seol-Hee Kim, Ji-Young Jang, Byong Chul Yoo, Chul Woo Kim & Choong-Eun Lee. BMB Reports 2022;55:198-203. https://doi.org/10.5483/BMBRep.2022.55.4.191

References

23

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

Hirohide Yoshikawa, Kenichi Matsubara, Geng-Sun Qian et al. · Nature Genetics · 2001 · 736 citations

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Inhibition of JAK1, 2/STAT3 Signaling Induces Apoptosis, Cell Cycle Arrest, and Reduces Tumor Cell Invasion in Colorectal Cancer Cells

Hua Xiong, Zhigang Zhang, Xiao-Qing Tian et al. · Neoplasia · 2008 · 432 citations · Full text

, , +17

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines

Ying Liu, Walter F. Bodmer · Proceedings of the National Academy of Sciences · 2006 · 252 citations

, , +15

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas

Geoffrey J. Lindeman, David Y.H. Choong, Sergio Wittlin et al. · Oncogene · 2004 · 220 citations

, , +15

Apoptosis in small intestinal epithelia from p53-null mice: evidence for a delayed, p53-indepdendent G2/M-associated cell death after γ-irradiation

Anita J. Merritt, Terence Allen, Christopher S. Potten et al. · Oncogene · 1997 · 213 citations

, , +16