Concepedia

<i>In vitro</i> evidence of oncofetal antigen and TLR-9 agonist co-delivery by alginate nanovaccines for liver cancer immunotherapy

Mengyue Pei, Huiyang Li, Yingwei Zhu, Jian Lü, Chuangnian Zhang

Biomaterials Science · 2022 · 14 citations · 25 references

DOI

Concepts

Abstract

histocompatibility showed that APPC was non-toxic within the tested concentration. This study demonstrates that the peptide antigen and the CpG adjuvant co-delivery nanovaccine have potential applications in liver cancer immunotherapy.

References

25

Cancer statistics, 2020

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2020 · 21.4K citations · Full text

, , +16

Nanoparticles target distinct dendritic cell populations according to their size

Vania Manolova, Anna Flace, Monika Bauer et al. · European Journal of Immunology · 2008 · 1.3K citations · Full text

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Critical Role for CD103+/CD141+ Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma

Edward W. Roberts, Miranda L. Broz, Mikhail Binnewies et al. · Cancer Cell · 2016 · 1K citations · Full text

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Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

Christopher Garris, Sean P. Arlauckas, Rainer H. Köhler et al. · Immunity · 2018 · 937 citations · Full text

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Enhanced antitumor immunity by targeting dendritic cells with tumor cell lysate-loaded chitosan nanoparticles vaccine

Gaona Shi, Chuangnian Zhang, Rong Xu et al. · Biomaterials · 2016 · 298 citations

, , +16