Sensitive sensing of alkaline phosphatase and γ-glutamyltranspeptidase activity for tumor imaging

Abstract

for GGT. Eventually, the BL probe P-Bz-Luc was successfully applied for sensitive imaging of the ALP and GGT co-overexpressed fLuc-231 breast cancer cells and tumors, with the help of the coordination cleavage of P-Bz-Luc by ALP and GGT.