Introduction of Lipophilic Side Chains to <i>N</i>H-Sulfoximines by Palladium Catalysis Under Blue Light Irradiation

Abstract

Palladium catalysis under blue (LED) light irradiation allows conversion of <i>N</i>H-sulfoximines into products with long lipophilic side chains attached to the S═N moiety. The three-component reactions involve both radicals and organometallic intermediates stemming from alkyl bromides and butadienes. The substrate scope is broad, and the products are formed in moderate to good yields.