Publication | Open Access
Evidence of co-infection during Delta and Omicron variants of concern co-circulation, weeks 49-2021 to 02-2022, France
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References
2022
Year
Unknown Venue
Virus EpidemiologyViral DiagnosticsDisease OutbreakCovid-19 EpidemiologyDual InfectionFifth WaveCovid-19Viral EvolutionClinical EpidemiologyDelta/omicron Sars-cov-2 Co-infectionsWeeks 49-2021Emerging Infectious DiseaseInfection ControlOmicron VariantsPublic HealthInfectious Disease EpidemiologyPathogen PrevalenceCovid-19 PandemicVirologyClinical MicrobiologyEpidemiologyVaccinationEmerging Infectious DiseasesPathogenesisConcern Co-circulationDisease TransmissionMedicine
Abstract We report evidence of Delta/Omicron SARS-CoV-2 co-infections during the fifth wave of COVID-19 pandemics in France for 7 immunocompetent and epidemiologically unrelated patients. These co-infections were detected by PCR assays targeting SARS-CoV-2 S-gene mutations K417N and L452R and confirmed by whole genome sequencing which allowed the proportion estimation of each subpopulation. For 2 patients, the analyses of longitudinal samples collected 7 to 11 days apart showed that Delta or Omicron can outcompete the other variant during dual infection.
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