Concepedia

Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on <i>ESKAPE</i> Bacterial Pathogens

Josefine Eilsø Nielsen, Morgan A. Alford, Deborah Bow Yue Yung, Natalia Molchanova, John A. Fortkort, Jennifer S Lin, Gill Diamond, Robert E. W. Hancock, Håvard Jenssen, Daniel Pletzer,

ACS Infectious Diseases · 2022 · 88 citations · 44 references

DOIFull text

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Concepts

Abstract

pathogens compared with peptoids that form ellipsoidal or bundled assemblies. This is the first report of self-assembling peptoid antibacterials with activity against in vivo biofilm-like infections relevant to clinical medicine.

References

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