Concepedia

Real-time <i>in vivo</i> imaging reveals specific nanoparticle target binding in a syngeneic glioma mouse model

Wenlong Zhang, Xiangyu Chen, Dong Ding, Guoxin Zhang, Ziwei Zhu, Xingjiu Yang, Mengyuan Li, Lijun Liang, Xudong Shi, Tie Wang,

Nanoscale · 2022 · 11 citations · 29 references

DOI

Concepts

Abstract

assay also confirmed the high binding affinity between GL-261-Tdtomato cells and SNPs-PEG-RGD-FITC. Our results indicate that SNPs-PEG-RGD-FITC has high penetration and retention in a solid glioma and our model provides novel ideas for the investigation of nanoparticle dynamics in brain tumors.

References

29

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Jeffrey J. Iliff, Minghuan Wang, Yonghong Liao et al. · Science Translational Medicine · 2012 · 5.6K citations · Full text

, , +16

Sleep Drives Metabolite Clearance from the Adult Brain

Lulu Xie, Hongyi Kang, Qiwu Xu et al. · Science · 2013 · 5.3K citations · Full text

, , +15

Real-time imaging reveals the single steps of brain metastasis formation

Yvonne Kienast, Louisa von Baumgarten, Martin Fuhrmann et al. · Nature Medicine · 2009 · 1.1K citations

, , +15

Brain tumour cells interconnect to a functional and resistant network

Matthias Osswald, Erik Jung, Felix Sahm et al. · Nature · 2015 · 1.1K citations

, , +14

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

Roger Stupp, Monika E. Hegi, Thierry Gorlia et al. · The Lancet Oncology · 2014 · 1K citations

, , +14