Biotechnology Reports · 2022 · 33 citations · 92 references
PharmacyInfectious DiseasesPharmacologyDrug DeliveryTargeted Drug DeliveryVirologyNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle DesignNanoparticle FormulationsAntiviral TherapeuticsImmune Evasion By NanoparticlesNeurological FunctionSars-cov-2 Antiviral ResistanceSars-cov-2 Antiviral TherapySars-cov-2 InfectionTargeted DeliveryTargeted Delivery Systems
Optimized therapeutic bio-compounds supported by bio-acceptable nanosystems (i.e., precise nanomedicine) have ability to promote health via maintaining body structure, organ function, and controlling chronic and acute effects. Therefore, nano-nutraceuticals (designed to neutralize virus, inhibit virus bindings with receptors, and support immunity) utilization can manage COVID-19 pre/post-infection effects. To explore these approaches well, our mini-review explores optimized bio-active compounds, their ability to influence SARS-CoV-2 infection, improvement in performance supported by precise nanomedicine approach, and challenges along with prospects. Such optimized pharmacologically relevant therapeutic cargo not only affect SARS-CoV-2 but will support other organs which show functional alternation due to SARS-CoV-2 for example, neurological functions. Hence, coupling the nutraceuticals with the nano-pharmacology perspective of higher efficacy via targeted delivery action can pave a novel way for health experts to plan future research needed to manage post COVID-19 infection effect where a longer efficacy with no side-effects is a key requirement.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang, Yeming Wang, Xingwang Li et al. · The Lancet · 2020 · 51.8K citations · Full text
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
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Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization
Tao Zuo, Fen Zhang, Grace Lui et al. · Gastroenterology · 2020 · 1.6K citations · Full text