Concepedia

Out-smarting smart drug modafinil through flow chemistry

Diana V. Silva-Brenes, Noémie Emmanuel, Vilmalí López-Mejías, Jorgé Duconge, Cornelis P. Vlaar, Torsten Stelzer, Jean‐Christophe M. Monbaliu

Green Chemistry · 2022 · 17 citations · 33 references

DOI

Concepts

Abstract

Intensified production of smart drug modafinil under continuous flow and sustainable conditions.

References

33

Green oxidation with aqueous hydrogen peroxide

Ryōji Noyori, Masayo Aoki, Kazuhiko Sato · Chemical Communications · 2003 · 1.1K citations

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system

Andrea Adamo, Rachel L. Beingessner, Mohsen Behnam et al. · Science · 2016 · 923 citations

EcoScale, a semi-quantitative tool to select an organic preparation based on economical and ecological parameters

Koen Van Aken, Lucjan Strękowski, Luc Patiny · Beilstein Journal of Organic Chemistry · 2006 · 689 citations · Full text

, , +15

End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

Salvatore Mascia, Patrick L. Heider, Haitao Zhang et al. · Angewandte Chemie International Edition · 2013 · 594 citations · Full text

Oxidation of sulfides to sulfoxides and sulfones with 30% hydrogen peroxide under organic solvent- and halogen-free conditions

Kazuhiko Sato, Mamoru Hyodo, Masao Aoki et al. · Tetrahedron · 2001 · 433 citations

, , +8