NEAR trial: A single-arm phase II trial of neoadjuvant apalutamide monotherapy and radical prostatectomy in intermediate- and high-risk prostate cancer - Concepedia

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NEAR trial: A single-arm phase II trial of neoadjuvant apalutamide monotherapy and radical prostatectomy in intermediate- and high-risk prostate cancer

DOI Full Paper Access

24

Citations

29

References

2022

Year

Lui Shiong Lee, Adelene Y. L. Sim, Chee Wee Ong, Xinyan Yang, Cedric Chuan Young Ng, Wei Liu, Vikneswari Rajasegaran, Abner Herbert Lim, Edwin Jonathan Aslim, Nye Thane Ngo,

Prostate Cancer and Prostatic Diseases

Abstract

A 12-week course of neoadjuvant apalutamide prior to RP did not meet the primary endpoint of pCR in this trial. Tumours with low androgen receptor activity or of the PAM50 basal subtype may have a reduced response to apalutamide.

References

	Year	Citations

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