Cathepsin K activity controls cachexia‐induced muscle atrophy via the modulation of IRS1 ubiquitination - Concepedia

Concepedia

Publication | Open Access

Cathepsin K activity controls cachexia‐induced muscle atrophy via the modulation of IRS1 ubiquitination

DOI Full Paper Access

23

Citations

31

References

2022

Year

Xiangkun Meng, Zhe Huang, Aiko Inoue, Hailong Wang, Ying Wan, Xueling Yue, Shengnan Xu, Xueying Jin, Guo‐Ping Shi, Masafumi Kuzuya,

Journal of Cachexia Sarcopenia and Muscle

Abstract

These results demonstrate that CTSK plays a novel role in IRS1 ubiquitination in LLC-induced muscle wasting, and suggest that CTSK could be an effective therapeutic target for cancer-related cachexia.

References

	Year	Citations

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