Quantitative Phosphoproteomics Reveals Extensive Protein Phosphorylation Dysregulation in the Cerebral Cortex of Huntington’s Disease Mice Prior to Onset of Symptoms

WGCNA: an R package for weighted correlation network analysis

Peter Langfelder, Steve Horvath · BMC Bioinformatics · 2008 · 29.1K citations · Full text

Life Sciences, Bioinformatics, Systems Biology +15

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments

Meena Choi, Ching-Yun Chang, Timothy Clough et al. · Bioinformatics · 2014 · 1.2K citations

Life Sciences, Bioinformatics, Biostatistics +17

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +17