TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8<sup>+</sup> T cell and XCR1<sup>+</sup> dendritic cell spatial co-localization - Concepedia

Concepedia

Publication | Open Access

TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8<sup>+</sup> T cell and XCR1<sup>+</sup> dendritic cell spatial co-localization

DOI Full Paper Access

45

Citations

37

References

2022

Year

Alycia Gardner, Álvaro de Mingo Pulido, Kay Hänggi, Sarah Bazargan, Alexis Onimus, Agnieszka Kasprzak, José R. Conejo-García, Katarzyna A. Rejniak, Brian Ruffell

Journal for ImmunoTherapy of Cancer

Abstract

TIM-3 blockade increases exposure of intratumoral CD8<sup>+</sup> T cells to cDC1-derived cytokines, with implications for the design of therapeutic strategies using antibodies against TIM-3.

References

	Year	Citations

Page 1