Concepedia

Thrombomodulin (THBD) gene variants and thrombotic risk in a population‐based cohort study

Eric Manderstedt, Christer Halldén, Christina Lind‐Halldén, Johan Elf, Peter J. Svensson, Gunnar Engström, Olle Melander, Aris Baras, Luca A. Lotta, Bengt Zöller

Journal of Thrombosis and Haemostasis · 2021 · 34 citations · 28 references

DOIFull text

Open access

Abstract

Rare qualifying THBD variants were associated with VTE, suggesting that rare variants in THBD contribute to development of VTE.

References

28

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

Kai Wang, Man Li, Håkon Håkonarson · Nucleic Acids Research · 2010 · 15.1K citations · Full text

, , +22

External review and validation of the Swedish national inpatient register

Jonas F. Ludvigsson, Eva Andersson, Anders Ekbom et al. · BMC Public Health · 2011 · 4.9K citations · Full text

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

Charles T. Esmon, Whyte G. Owen · Proceedings of the National Academy of Sciences · 1981 · 835 citations · Full text

, , +23

Deep Vein Thrombosis and Pulmonary Embolism in the General Population

Per‐Olof Hansson · Archives of Internal Medicine · 1997 · 346 citations

A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state.

Hartmut Weiler-Guettler, Patricia D. Christie, David Beeler et al. · Journal of Clinical Investigation · 1998 · 251 citations · Full text

, , +18