Concepedia

Publication | Open Access

Blunted sFasL signalling exacerbates TNF‐driven neutrophil necroptosis in critically ill COVID‐19 patients

DOIFull Paper Access

33

Citations

32

References

2021

Year

Tiziano A. Schweizer, Srikanth Mairpady Shambat, Clément Vulin, Sylvia Hoeller, Claudio Acevedo, Markus Huemer, Alejandro Gómez-Mejía, Chun‐Chi Chang, Jeruscha Baum, Sanne Hertegonne,
Clinical & Translational Immunology

Abstract

Our results suggest a novel role for sFasL signalling in the TNF-α-induced RCD programme in neutrophils during COVID-19 and a potential therapeutic target to curb inflammation and thus influence disease severity and outcome.

References

YearCitations

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