Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters

Clément Vulin, Nadja Leimer, Markus Huemer, +2

Nature Communications

Molecular reprogramming and phenotype switching in <i>Staphylococcus aureus</i> lead to high antibiotic persistence and affect therapy success

Markus Huemer, Srikanth Mairpady Shambat, Judith Bergadà-Pijuan, +13

Proceedings of the National Academy of Sciences

Targeting Hidden Pathogens: Cell-Penetrating Enzybiotics Eradicate Intracellular Drug-Resistant Staphylococcus aureus

Christian Röhrig, Markus Huemer, Dominique Lorgé, +14

mBio

Engineering of Long-Circulating Peptidoglycan Hydrolases Enables Efficient Treatment of Systemic Staphylococcus aureus Infection

Anna M. Sobieraj, Markus Huemer, Léa V. Zinsli, +8

mBio

Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA

Thomas P. Schmidt, Camilla Goetz, Markus Huemer, +1

Gut Pathogens

Blunted sFasL signalling exacerbates TNF‐driven neutrophil necroptosis in critically ill COVID‐19 patients

Tiziano A. Schweizer, Srikanth Mairpady Shambat, Clément Vulin, +15

Clinical & Translational Immunology

Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19

Srikanth Mairpady Shambat, Alejandro Gómez-Mejía, Tiziano A. Schweizer, +16

PLoS Pathogens

Innate Immune SystemImmunologyInnate ImmunityImmune SystemHost Immune Response +17

Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC 14579

Carmen M. Abfalter, Esther Schönauer, Karthe Ponnuraj, +8

PLoS ONE

True CollagenasesCollagenase ColaBacterial CollagenasesMicrobial PathogensEngineering +10

Quantification of within-patient Staphylococcus aureus phenotypic heterogeneity as a proxy for the presence of persisters across clinical presentations

Julian Bär, Mathilde Boumasmoud, Srikanth Mairpady Shambat, +13

Clinical Microbiology and Infection

Serine-threonine phosphoregulation by PknB and Stp contributes to quiescence and antibiotic tolerance in <i>Staphylococcus aureus</i>

Markus Huemer, Srikanth Mairpady Shambat, Sanne Hertegonne, +12

Science Signaling