Estimating the prognosis of esophageal squamous cell carcinoma based on The Cancer Genome Atlas (TCGA) of m6A methylation-associated genes

Abstract

We revealed three m6A methylation-associated genes that were closely correlated with enhanced survival in ESCC patients. In addition, we generated an independent prognostic signature based on the expression of <i>YTHDF3</i>, <i>RBM15</i>, <i>KIAA1429</i>, and <i>ALKBH5</i> genes. The results revealed significantly higher proportions of CD8⁺ T cells and higher expression of <i>PD-L1</i> in the H-R group.