Concepedia

Protective Effect of Rivaroxaban Against Amyloid Pathology and Neuroinflammation Through Inhibiting PAR-1 and PAR-2 in Alzheimer’s Disease Mice

Zhihong Bian, Xia Liu, Feng Tian, Haibo Yu, Xiao Hu, Xinran Hu, Yuting Bian, Hongming Sun, Koh Tadokoro, Mami Takemoto,

Journal of Alzheimer s Disease · 2022 · 14 citations · 37 references

DOI

Abstract

The present study demonstrates that rivaroxaban can attenuate AD progress and can be a potential choice to prevent AD.

References

37

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Koichiro Haruwaka, Ako Ikegami, Yoshihisa Tachibana et al. · Nature Communications · 2019 · 888 citations · Full text

Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

S A Heldt, Lisa M. Stanek, J P Chhatwal et al. · Molecular Psychiatry · 2007 · 670 citations · Full text

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In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939—an oral, direct Factor Xa inhibitor

Elisabeth Perzborn, Andreas Wilmen, Jens Pohlmann et al. · Journal of Thrombosis and Haemostasis · 2005 · 583 citations · Full text

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Guide to Receptors and Channels (GRAC), 3rd edition

S P H Alexander, Alistair Mathie, John A. Peters · British Journal of Pharmacology · 2008 · 508 citations · Full text

Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells

Hiroshi Kataoka, Justin R. Hamilton, David D. McKemy et al. · Blood · 2003 · 181 citations · Full text