Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

Leticia Corrales, Laura Hix Glickman, Sarah M. McWhirter et al. · Cell Reports · 2015 · 1.4K citations · Full text

Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death

Bridget Larkin, Vladimir Ilyukha, Maxim Sorokin et al. · The Journal of Immunology · 2017 · 338 citations · Full text

Innate Immune System, Immunology, Cell Death +18

Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response

Vijay K. Gonugunta, Tomomi Sakai, Vladislav Pokatayev et al. · Cell Reports · 2017 · 302 citations · Full text

EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCE

Dermot F. McGinnity, Matthew G. Soars, Richard A. Urbanowicz et al. · Drug Metabolism and Disposition · 2004 · 268 citations

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Jun Li, Mercedes A. Duran Paez, Ninjit Dhanota et al. · Cancer Discovery · 2020 · 264 citations · Full text