Protective role of mRNA demethylase FTO on axon guidance molecules of nigro-striatal projection system in manganese-induced parkinsonism

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Dan Dominissini, Sharon Moshitch-Moshkovitz, Schraga Schwartz et al. · Nature · 2012 · 4.9K citations

Chromatin, Natural Sciences, Genetics +8

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Guifang Jia, Ye Fu, Xu Zhao et al. · Nature Chemical Biology · 2011 · 4K citations

Nuclear Rna, Natural Sciences, Genetics +10

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

Sonja Kriks, Jaewon Shim, Jinghua Piao et al. · Nature · 2011 · 1.9K citations

Neurodegenerative Diseases, Neurobiology Of Disease, Synaptic Signaling +12

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Rui Su, Lei Dong, Chenying Li et al. · Cell · 2017 · 1.2K citations · Full text

Tumor Biology, Medicine, Tumor Suppressor +3

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

Yi Niu, Ziyou Lin, Arabella Wan et al. · Molecular Cancer · 2019 · 616 citations · Full text