World Journal of Clinical Cases · 2021 · 14 citations · 38 references
MedicineInfectious DiseasesClinical EpidemiologyEpidemiologyPulmonologyAcute Lung InjuryAcute Respiratory Distress SyndromeWeight ManagementAlbumin QuantificationCommunity-acquired Bacterial InfectionsLow Body Mass IndexObesity In Critical IllnessObesity-related MortalityPneumonia Severity AssessmentPrimary Outcome Analysis
BACKGROUND: Obesity is associated with a better prognosis in patients with community-acquired pneumonia (the so-called obesity survival paradox), but conflicting results have been found. AIM: To investigate the relationship between all-cause mortality and body mass index in patients with community-acquired pneumonia. METHODS: ). The primary outcome was all-cause hospital mortality. RESULTS: < 0.001) were independently associated with mortality. CONCLUSION: All-cause mortality of normal-weight patients was higher than overweight/ obesity patients, lower than that of underweight patients. Neutrophil counts, albumin levels, Confusion-Urea-Respiration-Blood pressure-65 score, and intensive care unit admission were independently associated with mortality in patients with community-acquired pneumonia.
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Obesity is associated with macrophage accumulation in adipose tissue
Stuart P. Weisberg, Daniel McCann, Manisha Desai et al. · Journal of Clinical Investigation · 2003 · 8.6K citations · Full text
Lionel A. Mandell, Richard G. Wunderink, Antonio Anzueto et al. · Clinical Infectious Diseases · 2007 · 6.2K citations · Full text