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Downregulation of TREM2 expression exacerbates neuroinflammatory responses through TLR4-mediated MAPK signaling pathway in a transgenic mouse model of Alzheimer’s disease

ImmunologyTransgenic Mouse ModelSynaptic SignalingNeuroinflammationInflammationAlzheimer's DiseaseDegenerative PathologyNeuroimmunologyCell SignalingMolecular SignalingTrem2 ExpressionBrain-immune InteractionNeurodegenerationCell BiologyNeurodegenerative DiseasesSignal TransductionNeuroinflammatory ResponsesNeuroscienceMolecular NeurobiologyMedicine