Concepedia

Cucurbitacin B regulates lung cancer cell proliferation and apoptosis <i>via</i> inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis

Jianhua Liu, Chen Li, Liang Cao, Changhong Zhang, Zhihua Zhang

Pharmaceutical Biology · 2021 · 47 citations · 37 references

DOIFull text

Open access

Abstract

CuB regulated cell proliferation and apoptosis by inhibiting the XIST/miR-let-7c/IL-6/STAT3 axis in lung cancer. These findings indicate CuB may have the possibility of clinical application in lung cancer treatment.

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