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Therapeutic Effect of IL-38 on Experimental Autoimmune Uveitis: Reprogrammed Immune Cell Landscape and Reduced Th17 Cell Pathogenicity

DOIFull Paper Access

20

Citations

31

References

2021

Year

He Li, Lei Zhu, Rong Wang, Lihui Xie, Yuxi Chen, Runping Duan, Xiuxing Liu, Zhaohao Huang, Binyao Chen, Zhaohuai Li,
Investigative Ophthalmology & Visual Science

Abstract

Our data demonstrate the therapeutic effect of IL-38 on EAU, and suggest that the effect of IL-38 may be caused by dampening of the GM-CSF/IL-23R/IL-23 feedback loop between Th17 cells and APCs.

References

YearCitations

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