Concepedia

Emodin Promotes Autophagy and Prevents Apoptosis in Sepsis-Associated Encephalopathy through Activating BDNF/TrkB Signaling

Lili Gao, Zhihao Wang, Yuhang Mu, Zuolong Liu, Li Pang

Pathobiology · 2021 · 54 citations · 38 references

DOIFull text

Open access

Abstract

Emodin significantly inhibited the progression of SAE via mediation of BDNF/TrkB signaling. Thus, Emodin might serve as a new agent for SAE treatment.

References

38

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Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah et al. · Autophagy · 2021 · 2.5K citations · Full text

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Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice

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Dexmedetomidine attenuates sepsis-associated inflammation and encephalopathy via central α2A adrenoceptor

Bin Mei, Jun Li, Zhiyi Zuo · Brain Behavior and Immunity · 2020 · 210 citations · Full text

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Xu Xie, Lu Liu, Yu-Chang Wang et al. · Brain Behavior and Immunity · 2019 · 210 citations

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