Concepedia

Publication | Open Access

Functional Analysis Identifies Damaging <i>CHEK2</i> Missense Variants Associated with Increased Cancer Risk

DOIFull Paper Access

53

Citations

54

References

2021

Year

Rick A.C.M. Boonen, Wouter W. Wiegant, Nandi Celosse, Bas Vroling, Stephan Heijl, Zsofia Kote‐Jarai, Martina Mijušković, Simona Cristea, Nienke Solleveld‐Westerink, Tom van Wezel,
Cancer Research

Abstract

Quantitative assessment of the functional consequences of CHEK2 variants of uncertain significance identifies damaging variants associated with increased cancer risk, which may aid in the clinical management of patients and carriers.

References

YearCitations

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