Stereoselective Palladium-Catalyzed Arylation of <i>Exo</i>-Glycals with Aryl Iodides

Abstract

A novel methodology for the arylation of exo-glycals has been developed. A range of exo-glycals underwent reactions with aryl iodides in the presence of a palladium catalyst. The transformation proceeded in a stereoselective manner to afford Z-isomers. The developed transformation demonstrated excellent functional group tolerance.