Concepedia

Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their chemotherapeutic potential

Gerhard Eisenbrand, Heinz H. Fiebig, W. Jens Zeller

Journal of Cancer Research and Clinical Oncology · 1976 · 40 citations · 17 references

DOI

Concepts

References

17

[Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

H. Druckrey, R. Preußmann, S. Ivanković et al. · PubMed · 1967 · 1.4K citations

, , +8

The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

John A. Montgomery, R Mccarthy James, G. S. MCCALEB et al. · Journal of Medicinal Chemistry · 1967 · 174 citations

, , +6

Interrelationships of some chemical, physicochemical, and biological activities of several 1-(2-haloethyl)-1-nitrosoureas.

Glynn P. Wheeler, Bonnie J. Bowdon, Jo Anne Grimsley et al. · PubMed · 1974 · 139 citations

, , +16

Interaction of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) with nucleic acids and proteins in vivo and in vitro.

S Fujimura, Dezider Grünberger, I B Weinstein · PubMed · 1972 · 121 citations

, , +7

The Synthesis of Potential Anticancer Agents. XXXVI. N-Nitrosoureas.<sup>1</sup> II. Haloalkyl Derivatives

Thomas P. Johnston, G. S. MCCALEB, Pamela S. Opliger et al. · Journal of Medicinal Chemistry · 1966 · 96 citations

, , +6