Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Harry Towbin, T. Staehelin, J. Gordon · Proceedings of the National Academy of Sciences · 1979 · 53.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Haider Raza, Annie John, Abderrahim Nemmar · Cellular Physiology and Biochemistry · 2013 · 47.3K citations · Full text

Life Sciences, Immunology, Toxicology +17

Molecular Cloning. A Laboratory Manual

EJ Wood · Biochemical Education · 1983 · 30.6K citations

Life Sciences, Molecular Biology, Molecular Genetics +13

DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

Stephen DiNardo, K Voelkel, Rolf Sternglanz · Proceedings of the National Academy of Sciences · 1984 · 685 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

Leroy F. Liu, Chen Liu, Bruce Alberts · Cell · 1980 · 546 citations

Life Sciences, Biochemistry, Molecular Biology +14