PubMed · 2007 · 32 citations · 10 references
BiologyHepatologyMedicineLiver PhysiologyEvolutionary BiologyHistopathologyForensic ToxicologyPathologyCypermethrin DoseNatural SciencesToxicologyHepatotoxicityEnvironmental ToxicologyExperimental ToxicologyPharmacologyHeteropneustes FossilisDrug-induced Liver InjuryChronic Concentration
Cypermethrin was administered to Heteropneustes fossilis in chronic concentration to determine lesion of liver as indicators of tissue damage. The cypermethrin dose used was 1/4 of 96 hr LC50. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and disposition of yellow brown grains at different time of exposure viz; 20th, 30th, 40th and 60th days.
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